Molecule Details
InChIKeyFRRLLRQAGKSVMU-SECBINFHSA-N
Compound NameBenzofuro[3,2-d]pyrimidin-4(3H)-one, 8-bromo-2-[[(3R)-3-hydroxy-1-pyrrolidinyl]methyl]-
Canonical SMILESO=c1[nH]c(CN2CC[C@@H](O)C2)nc2c1oc1ccc(Br)cc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL7.58
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
Q86V86 PIM3 Homo sapiens Human PF00069 8.4 IC50 ChEMBL;BindingDB
O00311 CDC7 Homo sapiens Human PF00069 8.3 IC50 ChEMBL;BindingDB
P11309 PIM1 Homo sapiens Human PF00069 8.1 IC50 ChEMBL;BindingDB
Q9P1W9 PIM2 Homo sapiens Human PF00069 7.2 IC50 ChEMBL;BindingDB
P68400 CSNK2A1 Homo sapiens Human PF00069 7.0 IC50 ChEMBL
P67870 CSNK2B Homo sapiens Human PF01214 7.0 IC50 ChEMBL
P19784 CSNK2A2 Homo sapiens Human PF00069 7.0 IC50 ChEMBL