Molecule Details
InChIKeyFREUQZHGBVWAQT-LNXUECGXSA-N
Canonical SMILESC[C@H]1CN(C)CCN1c1ccc(Nc2ncnc(-c3ccc(O[C@H]4CCN(C(=O)CO)C[C@H]4F)c(C#N)c3)n2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL7.72
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9UHD2 TBK1 Homo sapiens Human PF00069 PF18394 PF18396 8.7 IC50 BindingDB
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.7 IC50 ChEMBL;BindingDB