Molecule Details
| InChIKey | FRBRZGLUFOZRGD-YCMKEVRSSA-N |
|---|---|
| Compound Name | 4-(acetylamino)-3-fluoro-N-(trans-4-hydroxycyclohexyl)-5-[(1S)-1-phenylethoxy]benzamide |
| Canonical SMILES | CC(=O)Nc1c(F)cc(C(=O)NC2CCC(O)CC2)cc1O[C@@H](C)c1ccccc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.9 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O60885 | BRD4 | Homo sapiens | Human | PF17035 PF17105 PF00439 | 7.3 | IC50 | BindingDB |
| Q15059 | BRD3 | Homo sapiens | Human | PF17035 PF00439 | 7.0 | IC50 | BindingDB |
| Q58F21 | BRDT | Homo sapiens | Human | PF17035 PF17105 PF00439 | 6.7 | IC50 | BindingDB |
| P25440 | BRD2 | Homo sapiens | Human | PF17035 PF00439 | 6.6 | IC50 | BindingDB |