(2S)-1-[4-[3-methoxy-4-[[7-(2-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperazin-1-yl]propan-2-ol

InChIKey	`FQUQLTHTCSOGBY-IBGZPJMESA-N`
Compound Name	(2S)-1-[4-[3-methoxy-4-[[7-(2-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperazin-1-yl]propan-2-ol
Canonical SMILES	`COc1cc(N2CCN(C[C@H](C)O)CC2)ccc1Nc1ncc2ccc(-c3ccccc3OC)n2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.11
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UM73	ALK	Homo sapiens	Human	PF12810 PF00629 PF07714	7.7	IC50	ChEMBL;BindingDB
P06748	NPM1	Homo sapiens	Human	PF16276 PF03066	7.0	IC50	ChEMBL
P06213	INSR	Homo sapiens	Human	PF00757 PF17870 PF07714 PF01030	6.7	IC50	ChEMBL;BindingDB