Molecule Details
| InChIKey | FQHZXMKFQOKAPD-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-[[4-[3,5-Bis(cyclopropylmethoxy)phenyl]-7-(2-hydroxyethoxy)-6-methoxyquinazolin-2-yl]amino]propan-1-ol |
| Canonical SMILES | COc1cc2c(-c3cc(OCC4CC4)cc(OCC4CC4)c3)nc(NCCCO)nc2cc1OCCO |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.42 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 6.6 | IC50 | ChEMBL;BindingDB |
| Q13370 | PDE3B | Homo sapiens | Human | PF00233 | 6.4 | IC50 | ChEMBL |
| Q14432 | PDE3A | Homo sapiens | Human | PF00233 | 6.4 | IC50 | ChEMBL;BindingDB |
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 6.3 | IC50 | ChEMBL;BindingDB |