Molecule Details
InChIKeyFQEODTMNWMDUMD-UHFFFAOYSA-N
Compound Name5-[3-(2-methylpropyl)-1,2-oxazol-5-yl]-1H-indazol-3-amine
Canonical SMILESCC(C)Cc1cc(-c2ccc3[nH]nc(N)c3c2)on1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)25
Pfam Stratification Cross-Family
Avg pChEMBL6.66
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (25)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.9 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 7.9 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 7.6 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 7.3 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 6.9 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.8 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.8 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.8 Ki ChEMBL
P29597 TYK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.8 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.8 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 6.6 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.5 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.5 Ki ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.5 Ki ChEMBL
Q7KZI7 MARK2 Homo sapiens Human PF02149 PF00069 PF00627 6.4 Ki ChEMBL
Q96KB5 PBK Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.3 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.3 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.1 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.0 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.0 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.0 Ki ChEMBL