6-Amino-4-(2-iodophenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

InChIKey	`FQBWBTKXLRVHDG-UHFFFAOYSA-N`
Compound Name	6-Amino-4-(2-iodophenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
Canonical SMILES	`Cc1n[nH]c2c1C(c1ccccc1I)C(C#N)=C(N)O2`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.47
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P17948	FLT1	Homo sapiens	Human	PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	6.7	Ki	ChEMBL
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	6.5	Ki	ChEMBL
P08922	ROS1	Homo sapiens	Human	PF00041 PF07714	6.2	Ki	ChEMBL