InChIKey	FPVKHBSQESCIEP-JQCXWYLXSA-N
Compound Name	Pentostatin
Canonical SMILES	OC[C@H]1O[C@@H](n2cnc3c2NC=NC[C@H]3O)C[C@@H]1O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	9.87
Source	BindingDB;ChEMBL

DrugBank ID	DB00552
Drug Name	Pentostatin
CAS Number	53910-25-1
Groups	approved investigational
ATC Codes	L01XX08
Description	A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.

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Categories: Adenosine Deaminase Inhibitors Antineoplastic Agents Antineoplastic and Immunomodulating Agents Cancer immunotherapy Cardiotoxic antineoplastic agents Coformycin Deoxyribonucleosides Drugs that are Mainly Renally Excreted Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index Enzyme Inhibitors Formycins Immunosuppressive Agents Immunotherapy Myelosuppressive Agents Narrow Therapeutic Index Drugs Nucleic Acid Synthesis Inhibitors Nucleic Acids, Nucleotides, and Nucleosides Nucleoside Metabolic Inhibitor Nucleosides Pyrimidine Nucleosides Pyrimidines

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Cross-references: BindingDB: 22925 ChEBI: 27834 CHEMBL1580 ChemSpider: 388759 Drugs Product Database (DPD): 1740 C02267 D00155 PDB: DCF PharmGKB: PA450863 PubChem:439693 PubChem:46507116 RxCUI: 8011 Therapeutic Targets Database: DAP000566 Wikipedia: Pentostatin ZINC: ZINC000003806262