1,3,5-Triazine-2,4-diamine, 1-(3,4-dichlorophenyl)-1,6-dihydro-6,6-dimethyl-

InChIKey	`FPULLBVUFHTKQQ-UHFFFAOYSA-N`
Compound Name	1,3,5-Triazine-2,4-diamine, 1-(3,4-dichlorophenyl)-1,6-dihydro-6,6-dimethyl-
Canonical SMILES	`CC1(C)N=C(N)N=C(N)N1c1ccc(Cl)c(Cl)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.29
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00374	DHFR	Homo sapiens	Human	PF00186	7.0	Ki	ChEMBL;BindingDB
A7UD81	DHFR-TS	Plasmodium falciparum	Pathogen	PF00186 PF00303	9.0	Ki	BindingDB
P13922		Plasmodium falciparum (isolate K1 / Thailand)	Pathogen	PF00186 PF00303	9.0	Ki	ChEMBL;BindingDB