Molecule Details
InChIKeyFPQHXFMYXQZPSV-UHFFFAOYSA-N
Compound NameN-{[(4-chlorophenyl)carbamothioyl]amino}-2-hydroxy-2,2-diphenylacetamide
Canonical SMILESO=C(NNC(=S)Nc1ccc(Cl)cc1)C(O)(c1ccccc1)c1ccccc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)23
Pfam Stratification Cross-Family
Avg pChEMBL6.3
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (23)
Target Gene Organism Category Pfam pChEMBL Type Source
O43781 DYRK3 Homo sapiens Human PF00069 7.1 Ki ChEMBL
Q96SB4 SRPK1 Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q96KB5 PBK Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q8IW41 MAPKAPK5 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.5 Ki ChEMBL
P30530 AXL Homo sapiens Human PF00041 PF13927 PF07714 6.4 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.4 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.2 Ki ChEMBL
P51955 NEK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.1 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.1 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
Q9H4B4 PLK3 Homo sapiens Human PF00069 PF00659 6.1 Ki ChEMBL
Q9NR20 DYRK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9BWU1 CDK19 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 6.0 Ki ChEMBL