Molecule Details
| InChIKey | FOZFBBKUKXGMND-UHFFFAOYSA-N |
|---|---|
| Compound Name | US10092575, Example 141 |
| Canonical SMILES | COc1ccc(Cn2c(=O)n3ncnc3c3c4c(sc32)CN(CC2CCOCC2)CC4)c(F)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.0 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P54750 | PDE1A | Homo sapiens | Human | PF00233 PF08499 | 7.6 | IC50 | ChEMBL |
| Q01064 | PDE1B | Homo sapiens | Human | PF00233 PF08499 | 7.6 | IC50 | ChEMBL;BindingDB |
| Q14123 | PDE1C | Homo sapiens | Human | PF00233 PF08499 | 7.6 | IC50 | ChEMBL |
| O76074 | PDE5A | Homo sapiens | Human | PF01590 PF00233 | 6.6 | IC50 | ChEMBL;BindingDB |
| Q9HCR9 | PDE11A | Homo sapiens | Human | PF01590 PF00233 | 6.5 | IC50 | ChEMBL;BindingDB |
| Q9Y233 | PDE10A | Homo sapiens | Human | PF01590 PF00233 | 6.2 | IC50 | ChEMBL;BindingDB |