Molecule Details
| InChIKey | FOIVPCKZDPCJJY-JQIJEIRASA-N |
|---|---|
| Compound Name | Arotinoid acid |
| Canonical SMILES | C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.78 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB02877 |
|---|---|
| Drug Name | Arotinoid acid |
| CAS Number | 71441-28-6 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Arotinoid acid is a retinoic acid analog which acts as a selective RAR agonist. |
Categories: Acids, Carbocyclic Alkenes Benzene Derivatives Biological Factors Carotenoids Cyclohexanes Cyclohexenes Cycloparaffins Hydrocarbons, Acyclic Pigments, Biological Polyenes Terpenes
Cross-references: BindingDB: 50032219 ChEBI: 75261 CHEMBL275311 ChemSpider: 4451454 Guide to Pharmacology: 2646 IUPHAR: 2646 C15634 PDB: TTB PubChem:5289501 PubChem:46507753 ZINC: ZINC000004475360
Target Activities (3)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P10826 | RARB | Retinoic acid receptor beta | inhibitor | targets |