Molecule Details
InChIKeyFNTHJTUPRVAXFZ-UHFFFAOYSA-N
Compound Name1-(3,4-Dichlorophenyl)-3-[(2-hydroxybenzoyl)amino]thiourea
Canonical SMILESO=C(NNC(=S)Nc1ccc(Cl)c(Cl)c1)c1ccccc1O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)17
Pfam Stratification Cross-Family
Avg pChEMBL7.68
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (17)
Target Gene Organism Category Pfam pChEMBL Type Source
P00734 F2 Homo sapiens Human PF00594 PF00051 PF09396 PF00089 10.0 IC50 ChEMBL;BindingDB
P21554 CNR1 Homo sapiens Human PF00001 9.2 IC50 ChEMBL;BindingDB
P08908 HTR1A Homo sapiens Human PF00001 9.2 IC50 ChEMBL;BindingDB
P12821 ACE Homo sapiens Human PF01401 9.2 IC50 ChEMBL;BindingDB
P23219 PTGS1 Homo sapiens Human PF03098 8.1 IC50 ChEMBL;BindingDB
P11229 CHRM1 Homo sapiens Human PF00001 7.7 IC50 ChEMBL;BindingDB
P00918 CA2 Homo sapiens Human PF00194 7.5 IC50 ChEMBL;BindingDB
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 7.5 IC50 ChEMBL;BindingDB
P21397 MAOA Homo sapiens Human PF01593 7.4 IC50 ChEMBL;BindingDB
Q07869 PPARA Homo sapiens Human PF00104 PF00105 7.3 IC50 ChEMBL;BindingDB
P14867 GABRA1 Homo sapiens Human PF02931 PF02932 7.1 IC50 ChEMBL;BindingDB
P18507 GABRG2 Homo sapiens Human PF02931 PF02932 7.1 IC50 ChEMBL
P47870 GABRB2 Homo sapiens Human PF02931 PF02932 7.1 IC50 ChEMBL
Q12809 KCNH2 Homo sapiens Human PF00027 PF00520 PF13426 7.1 IC50 ChEMBL;BindingDB
Q99685 MGLL Homo sapiens Human PF12146 6.4 IC50 ChEMBL;BindingDB
Q14432 PDE3A Homo sapiens Human PF00233 6.3 IC50 ChEMBL;BindingDB
P22303 ACHE Homo sapiens Human PF08674 PF00135 6.3 IC50 ChEMBL;BindingDB