Molecule Details
| InChIKey | FNRUBUFCNWKZEI-UHFFFAOYSA-N |
|---|---|
| Compound Name | US11472805, Example 16 |
| Canonical SMILES | Cc1cc(C#N)c(F)cc1-c1c2c(n3c1C(=O)N(C1CC1)CC3)CCCO2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.18 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 8.8 | IC50 | ChEMBL;BindingDB |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 8.8 | IC50 | BindingDB |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 7.8 | IC50 | BindingDB |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 7.3 | IC50 | BindingDB |