N-(2-(2-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-ylamino)thiazol-5-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine

InChIKey	`FNECROKREKHEJS-UHFFFAOYSA-N`
Compound Name	N-(2-(2-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-ylamino)thiazol-5-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine
Canonical SMILES	`FC(F)(F)c1ccc2nc(Nc3ncc(CCNc4ncnc5ccsc45)s3)[nH]c2c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.28
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O14965	AURKA	Homo sapiens	Human	PF00069	6.3	IC50	ChEMBL;BindingDB
O75716	STK16	Homo sapiens	Human	PF00069	6.3	pIC50	TTD_MultiTarget
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.2	IC50	ChEMBL;BindingDB