Cyclo-(phe-arg-gly-asp-leu-ala-phe-D-pro-(nme)lys)

InChIKey	`FLTIMXZSLYRKOV-QPFBIXMUSA-N`
Compound Name	Cyclo-(phe-arg-gly-asp-leu-ala-phe-D-pro-(nme)lys)
Canonical SMILES	`CC(C)C[C@@H]1NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)N(C)C(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC1=O`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	6
Pfam Stratification	Cross-Family
Avg pChEMBL	7.55
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P18564	ITGB6	Homo sapiens	Human	PF07974 PF23105 PF18372 PF08725 PF07965 PF00362 PF17205	9.6	IC50	ChEMBL;BindingDB
P06756	ITGAV	Homo sapiens	Human	PF01839 PF08441 PF20805 PF20806 PF00357	7.6	IC50	ChEMBL
P26012	ITGB8	Homo sapiens	Human	PF23105 PF23106 PF00362 PF17205	7.6	IC50	ChEMBL;BindingDB
P05556	ITGB1	Homo sapiens	Human	PF07974 PF23105 PF18372 PF08725 PF07965 PF00362 PF17205	7.1	IC50	ChEMBL
P08648	ITGA5	Homo sapiens	Human	PF01839 PF08441 PF20805 PF20806	7.1	IC50	ChEMBL;BindingDB
P05106	ITGB3	Homo sapiens	Human	PF07974 PF23105 PF18372 PF08725 PF07965 PF00362 PF17205	6.2	IC50	ChEMBL;BindingDB