Molecule Details
| InChIKey | FLJAMCIHLYTQCT-UHFFFAOYSA-N |
|---|---|
| Compound Name | [3-(Furan-2-yl)-5-methylsulfanyl-1,2,4-triazol-1-yl]-(2-methoxyphenyl)methanone |
| Canonical SMILES | COc1ccccc1C(=O)n1nc(-c2ccco2)nc1SC |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.6 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00734 | F2 | Homo sapiens | Human | PF00594 PF00051 PF09396 PF00089 | 9.0 | IC50 | ChEMBL;BindingDB |
| P03951 | F11 | Homo sapiens | Human | PF00024 PF00089 | 7.5 | IC50 | BindingDB |
| Q9Y337 | KLK5 | Homo sapiens | Human | PF00089 | 7.1 | IC50 | BindingDB |
| P00748 | F12 | Homo sapiens | Human | PF00008 PF00039 PF00040 PF00051 PF00089 | 6.8 | IC50 | BindingDB |