Molecule Details
| InChIKey | FLCHMGRFSJQORK-UHFFFAOYSA-N |
|---|---|
| Compound Name | 7,8,17-Triazatetracyclo[12.2.1.05,16.09,15]heptadeca-1,3,5(16),8,14-pentaen-6-one |
| Canonical SMILES | O=C1NN=C2CCCCc3[nH]c4cccc1c4c32 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.98 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9UGN5 | PARP2 | Homo sapiens | Human | PF00644 PF02877 PF05406 | 9.0 | IC50 | ChEMBL;BindingDB |
| P09874 | PARP1 | Homo sapiens | Human | PF00533 PF21728 PF00644 PF02877 PF05406 PF00645 PF08063 | 8.2 | IC50 | ChEMBL;BindingDB |
| Q9H2K2 | TNKS2 | Homo sapiens | Human | PF00023 PF12796 PF13637 PF00644 PF07647 | 6.8 | IC50 | ChEMBL;BindingDB |