Molecule Details
InChIKeyFJZXDUKUMALHNP-UHFFFAOYSA-N
Compound Name1-(4-(5-Aminoquinoxalin-6-yl)phenyl)-3-m-tolylurea
Canonical SMILESCc1cccc(NC(=O)Nc2ccc(-c3ccc4nccnc4c3N)cc2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.76
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 8.2 Ki ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 7.6 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.3 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.8 IC50 ChEMBL;BindingDB
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.5 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.5 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.4 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.2 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.0 Ki ChEMBL