Molecule Details
InChIKeyFIVPIPIDMRVLAY-RBJBARPLSA-N
Compound NameGliotoxin
Canonical SMILESCN1C(=O)[C@]23CC4=CC=C[C@H](O)[C@H]4N2C(=O)[C@@]1(CO)SS3
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.41
SourceChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
O43463 SUV39H1 Homo sapiens Human PF00385 PF05033 PF00856 6.6 IC50 ChEMBL
Q96EP0 RNF31 Homo sapiens Human PF18091 PF22191 PF09409 PF18486 PF16678 PF25163 6.3 IC50 ChEMBL
Q9BYM8 RBCK1 Homo sapiens Human PF25393 PF13445 6.3 IC50 ChEMBL
Q9H0F6 SHARPIN Homo sapiens Human PF25393 PF16764 6.3 IC50 ChEMBL
Q96KQ7 EHMT2 Homo sapiens Human PF00023 PF12796 PF21533 PF05033 PF00856 6.3 IC50 ChEMBL
P49354 FNTA Homo sapiens Human PF01239 Clinical TTD_MultiTarget TTD_MultiTarget
P07342 ILV2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Pathogen PF02775 PF00205 PF02776 6.7 IC50 ChEMBL