3-Pyridinecarboxylic acid, 5-[[[3-(4,4-diphenyl-1-piperidinyl)propyl]amino]carbonyl]-1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-, methyl ester

InChIKey	`FIIXCJGBCCCOQQ-UHFFFAOYSA-N`
Compound Name	3-Pyridinecarboxylic acid, 5-[[[3-(4,4-diphenyl-1-piperidinyl)propyl]amino]carbonyl]-1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-, methyl ester
Canonical SMILES	`COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	5
Pfam Stratification	Homologous
Avg pChEMBL	6.97
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P35348	ADRA1A	Homo sapiens	Human	PF00001	9.5	Ki	ChEMBL
P35368	ADRA1B	Homo sapiens	Human	PF00001	6.7	Ki	ChEMBL
P18825	ADRA2C	Homo sapiens	Human	PF00001	6.4	Ki	ChEMBL
P25100	ADRA1D	Homo sapiens	Human	PF00001	6.3	Ki	ChEMBL
P18089	ADRA2B	Homo sapiens	Human	PF00001	6.1	Ki	ChEMBL