Molecule Details
| InChIKey | FICBCKOSWMLHMT-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-(3,4-difluorophenyl)-3-[3-(4-oxo-3H-quinazolin-7-yl)phenyl]urea |
| Canonical SMILES | O=C(Nc1cccc(-c2ccc3c(=O)[nH]cnc3c2)c1)Nc1ccc(F)c(F)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.58 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q02763 | TEK | Homo sapiens | Human | PF00041 PF10430 PF07714 | 7.8 | IC50 | ChEMBL;BindingDB |
| P35968 | KDR | Homo sapiens | Human | PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 | 7.5 | IC50 | ChEMBL;BindingDB |
| P54760 | EPHB4 | Homo sapiens | Human | PF14575 PF25599 PF01404 PF07699 PF00041 PF07714 PF00536 | 7.4 | IC50 | ChEMBL;BindingDB |