2-[(2,2-Difluoroethyl)[[5-[[6-methyl-3-(1Hpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-isothiazolyl]methyl]-amino]-2-methyl-1-propanol Hydrochloride

InChIKey	`FHRXTSQACPDPRQ-UHFFFAOYSA-N`
Compound Name	2-[(2,2-Difluoroethyl)[[5-[[6-methyl-3-(1Hpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-isothiazolyl]methyl]-amino]-2-methyl-1-propanol Hydrochloride
Canonical SMILES	`Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN(CC(F)F)C(C)(C)CO)ns2)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.46
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O75716	STK16	Homo sapiens	Human	PF00069	8.4	pIC50	TTD_MultiTarget
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.5	IC50	ChEMBL;BindingDB