Molecule Details
| InChIKey | FHJXPRTVVWNFEW-HSZRJFAPSA-N |
|---|---|
| Compound Name | (R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-methyl-5-(3-methylamino-propane-1-sulfonyl)-1H-imidazo[1,2-a]imidazol-2-one |
| Canonical SMILES | CNCCCS(=O)(=O)c1cnc2n1[C@](C)(Cc1ccc(Br)cc1)C(=O)N2c1cc(Cl)cc(Cl)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.82 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P05107 | ITGB2 | Homo sapiens | Human | PF23105 PF08725 PF07965 PF00362 PF17205 | 6.8 | Kd | ChEMBL |
| P05362 | ICAM1 | Homo sapiens | Human | PF21146 PF03921 PF13895 | 6.8 | Kd | ChEMBL |
| P20701 | ITGAL | Homo sapiens | Human | PF01839 PF08441 PF20805 PF00357 PF00092 | 6.8 | Kd | ChEMBL;BindingDB |