Molecule Details
InChIKeyFHCSBLWRGCOVPT-UHFFFAOYSA-N
Compound NameAzd2858
Canonical SMILESCN1CCN(S(=O)(=O)c2ccc(-c3cnc(N)c(C(=O)Nc4cccnc4)n3)cc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Cross-Family
Avg pChEMBL6.78
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
P49841 GSK3B Homo sapiens Human PF00069 8.3 IC50 ChEMBL;BindingDB
O96020 CCNE2 Homo sapiens Human PF02984 PF00134 6.3 Ki ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 6.3 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL