Molecule Details
| InChIKey | FHAJFFRLMGECJB-SLJXGACLSA-N |
|---|---|
| Compound Name | (2S)-2-benzyl-3-[[(2S)-2-benzyl-3-[[(1S,2R)-2-hydroxyindan-1-yl]amino]-3-oxo-propyl]-dihydroxy-silyl]-N-[(1S,2R)-2-hydroxyindan-1-yl]propanamide |
| Canonical SMILES | O=C(N[C@H]1c2ccccc2C[C@H]1O)[C@H](Cc1ccccc1)C[Si](O)(O)C[C@@H](Cc1ccccc1)C(=O)N[C@H]1c2ccccc2C[C@H]1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.57 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (2)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P12497 | gag-pol | Human immunodeficiency virus type 1 group M subtype B (isolate NY5) | Pathogen | PF00540 PF19317 PF00552 PF02022 PF00075 PF00665 PF00077 PF00078 PF06815 PF06817 PF00098 | 8.6 | Ki | BindingDB |
| Q9YQ12 | protease | Human immunodeficiency virus type 1 | Pathogen | PF00077 | 8.6 | Ki | ChEMBL |