Molecule Details
InChIKeyFGWOKLCRQJXPPQ-UHFFFAOYSA-N
Compound NameN-(cyclopropylmethyl)-4-[2-(4-fluorophenyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-amine
Canonical SMILESFc1ccc(-c2nc3cnccn3c2-c2ccnc(NCC3CC3)n2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Cross-Family
Avg pChEMBL6.51
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
P48730 CSNK1D Homo sapiens Human PF00069 8.1 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 7.3 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.8 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.7 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.6 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.4 Ki ChEMBL
P42685 FRK Homo sapiens Human PF07714 PF00017 PF00018 6.3 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.2 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.2 Ki ChEMBL
Q9NYL2 MAP3K20 Homo sapiens Human PF07714 PF07647 6.1 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 6.0 Ki ChEMBL