Molecule Details
InChIKeyFFMRDJNJHCWRIX-UHFFFAOYSA-N
Compound Name4-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-1-(1-methyl-1H-pyrazol-5-yl)-4,5-dihydropyrrolo-[3,4-c]pyrazol-6(1H)-one
Canonical SMILESCc1cc(N2C(=O)c3c(c(C4CC4)nn3-c3ccnn3C)C2c2ccc(Cl)cc2)cn2c(C)nnc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.43
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P25440 BRD2 Homo sapiens Human PF17035 PF00439 7.5 IC50 ChEMBL;BindingDB
Q15059 BRD3 Homo sapiens Human PF17035 PF00439 7.4 IC50 ChEMBL;BindingDB
O60885 BRD4 Homo sapiens Human PF17035 PF17105 PF00439 7.4 IC50 ChEMBL;BindingDB