Molecule Details
InChIKeyFFLJVBPCONQSQW-UHFFFAOYSA-N
Compound Name6-(4-Piperazin-1-ylphenyl)-3-quinolin-4-ylfuro[3,2-b]pyridine
Canonical SMILESc1ccc2c(-c3coc4cc(-c5ccc(N6CCNCC6)cc5)cnc34)ccnc2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL6.92
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
P37023 ACVRL1 Homo sapiens Human PF07714 PF08515 7.9 IC50 ChEMBL
P36896 ACVR1B Homo sapiens Human PF01064 PF00069 PF08515 7.6 IC50 ChEMBL
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 7.4 IC50 ChEMBL
O00238 BMPR1B Homo sapiens Human PF01064 PF07714 PF08515 7.4 IC50 ChEMBL
P36894 BMPR1A Homo sapiens Human PF01064 PF07714 PF08515 6.4 IC50 ChEMBL
Q08345 DDR1 Homo sapiens Human PF21114 PF00754 PF07714 6.3 IC50 ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.3 IC50 ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.1 IC50 ChEMBL