Molecule Details
InChIKeyFEKRWNWZMOSVBX-UHFFFAOYSA-O
Compound Name6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-carboxamidine
Canonical SMILESNC(=[NH2+])c1cc2cc(-c3cccc(-c4ccccc4)c3O)[nH]c2cc1Cl
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL6.99
SourceBindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB03865
Drug Name6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 14152 ChemSpider: 393359 PDB: 132 PubChem:445843 PubChem:46507457
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P00749 PLAU Homo sapiens Human PF00051 PF00089 7.9 Ki BindingDB
P00747 PLG Homo sapiens Human PF00051 PF00024 PF00089 7.0 Ki BindingDB
P07477 PRSS1 Homo sapiens Human PF00089 6.1 Ki BindingDB
DrugBank Target Actions (4)
Target Gene Target Name Action Type
P00734 F2 Prothrombin binder targets
P00749 PLAU Urokinase-type plasminogen activator binder targets
P05981 HPN Serine protease hepsin binder targets
P07477 PRSS1 Serine protease 1 binder targets