Molecule Details
InChIKeyFEKRWNWZMOSVBX-UHFFFAOYSA-N
Compound Name6-chloro-2-(2-hydroxybiphenyl-3-yl)-1H-indole-5-carboxamidine
Canonical SMILESN=C(N)c1cc2cc(-c3cccc(-c4ccccc4)c3O)[nH]c2cc1Cl
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Homologous
Avg pChEMBL6.84
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P00749 PLAU Homo sapiens Human PF00051 PF00089 8.1 Ki ChEMBL;BindingDB
P00750 PLAT Homo sapiens Human PF00008 PF00039 PF00051 PF00089 7.0 Ki ChEMBL;BindingDB
P07477 PRSS1 Homo sapiens Human PF00089 6.6 Ki ChEMBL;BindingDB
P07478 PRSS2 Homo sapiens Human PF00089 6.6 Ki ChEMBL
P35030 PRSS3 Homo sapiens Human PF00089 6.6 Ki ChEMBL
P03952 KLKB1 Homo sapiens Human PF00024 PF00089 6.1 Ki ChEMBL