Molecule Details
| InChIKey | FCCJIRJUDAWXRO-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]pyridin-2-yl]cyclopropanecarboxamide |
| Canonical SMILES | O=C(CNc1ccc(-c2ccc(NC(=O)C3CC3)nc2)cc1)Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.98 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9HBH9 | MKNK2 | Homo sapiens | Human | PF00069 | 8.1 | IC50 | ChEMBL;BindingDB |
| P00519 | ABL1 | Homo sapiens | Human | PF08919 PF07714 PF00017 PF00018 | 6.8 | IC50 | ChEMBL;BindingDB |
| P11274 | BCR | Homo sapiens | Human | PF09036 PF00168 PF19057 PF00620 PF00621 | 6.7 | IC50 | ChEMBL |
| Q9BUB5 | MKNK1 | Homo sapiens | Human | PF00069 | 6.3 | IC50 | ChEMBL;BindingDB |