Molecule Details
InChIKeyFBTRDJIPJVBTHV-HNNXBMFYSA-N
Compound NameMNK inhibitor 9
Canonical SMILESC[C@H]1CN(c2cccc3nc(-c4nc(-c5cc(C(=O)N(C)C)ccn5)cnc4N)n(C)c23)CCN1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.05
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9BUB5 MKNK1 Homo sapiens Human PF00069 8.5 IC50 ChEMBL;BindingDB
Q9HBH9 MKNK2 Homo sapiens Human PF00069 8.5 IC50 ChEMBL;BindingDB
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.5 IC50 ChEMBL;BindingDB
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.4 IC50 ChEMBL;BindingDB
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.2 IC50 ChEMBL;BindingDB
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.1 IC50 ChEMBL;BindingDB