2-[4-[3-methoxy-4-[[7-(2-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]-N-methylacetamide

InChIKey	`FAUWHVUDSIQEKF-UHFFFAOYSA-N`
Compound Name	2-[4-[3-methoxy-4-[[7-(2-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]-N-methylacetamide
Canonical SMILES	`CNC(=O)CN1CCC(c2ccc(Nc3ncc4ccc(-c5ccccc5OC)n4n3)c(OC)c2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.1
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UM73	ALK	Homo sapiens	Human	PF12810 PF00629 PF07714	7.5	IC50	ChEMBL;BindingDB
P06748	NPM1	Homo sapiens	Human	PF16276 PF03066	7.0	IC50	ChEMBL
P06213	INSR	Homo sapiens	Human	PF00757 PF17870 PF07714 PF01030	6.8	IC50	ChEMBL;BindingDB