2-(cyclohexylamino)-4-pyridin-4-yl-1H-pyrimidin-6-one

InChIKey	`FAIHBCXQSBIRIL-UHFFFAOYSA-N`
Compound Name	2-(cyclohexylamino)-4-pyridin-4-yl-1H-pyrimidin-6-one
Canonical SMILES	`O=c1cc(-c2ccncc2)nc(NC2CCCCC2)[nH]1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	22
Pfam Stratification	Cross-Family
Avg pChEMBL	6.7
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UBU7	DBF4	Homo sapiens	Human	PF07535	8.7	Ki	ChEMBL;BindingDB
O00311	CDC7	Homo sapiens	Human	PF00069	8.7	Ki	ChEMBL
Q9HAZ1	CLK4	Homo sapiens	Human	PF00069	7.7	Ki	ChEMBL
Q13627	DYRK1A	Homo sapiens	Human	PF00069	7.4	Ki	ChEMBL
P50750	CDK9	Homo sapiens	Human	PF00069	7.3	Ki	ChEMBL
Q9H2X6	HIPK2	Homo sapiens	Human	PF00069	7.1	Ki	ChEMBL
P49840	GSK3A	Homo sapiens	Human	PF00069	6.8	Ki	ChEMBL
P49841	GSK3B	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.6	Ki	ChEMBL
O75116	ROCK2	Homo sapiens	Human	PF25346 PF00069 PF08912	6.4	Ki	ChEMBL
O95819	MAP4K4	Homo sapiens	Human	PF00780 PF00069	6.3	Ki	ChEMBL
P48730	CSNK1D	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
P49760	CLK2	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
P51617	IRAK1	Homo sapiens	Human	PF00531 PF00069	6.3	Ki	ChEMBL
P06493	CDK1	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
P48729	CSNK1A1	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
P50613	CDK7	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
O43781	DYRK3	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL
Q00535	CDK5	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL
Q8NE63	HIPK4	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL
Q12851	MAP4K2	Homo sapiens	Human	PF00780 PF00069	6.0	Ki	ChEMBL
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	6.0	Ki	ChEMBL