Molecule Details
| InChIKey | DZVJBZTUTCHLSB-ZOZMAKRUSA-N |
|---|---|
| Compound Name | (3R)-3-((3-((2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)methyl)-8-azabicyclo[3.2.1]octan-8-yl)methyl)-7,9-dihydro-2H-[1,4]dioxino[2,3-e]indol-8(3H)-one |
| Canonical SMILES | O=C1CCc2ccc(CC3CC4CCC(C3)N4C[C@@H]3COc4c(ccc5c4CC(=O)N5)O3)cc2N1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.34 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P31645 | SLC6A4 | Homo sapiens | Human | PF03491 PF00209 | 9.6 | Ki | ChEMBL;BindingDB |
| P25100 | ADRA1D | Homo sapiens | Human | PF00001 | 8.1 | Ki | ChEMBL |
| P35348 | ADRA1A | Homo sapiens | Human | PF00001 | 8.1 | Ki | ChEMBL |
| P35368 | ADRA1B | Homo sapiens | Human | PF00001 | 8.1 | Ki | ChEMBL |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 7.8 | Ki | ChEMBL;BindingDB |