Molecule Details
InChIKeyDZGATJHVQUFYSK-UHFFFAOYSA-N
Compound Name4-[4-(1,3-Benzoxazol-2-ylamino)phenyl]-6-[3-(dimethylamino)propoxy]-2,3-dihydroisoindol-1-one
Canonical SMILESCN(C)CCCOc1cc2c(c(-c3ccc(Nc4nc5ccccc5o4)cc3)c1)CNC2=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL6.25
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.7 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.5 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.4 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.3 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.3 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.2 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.2 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.1 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P15735 PHKG2 Homo sapiens Human PF00069 6.0 Ki ChEMBL