1-[4-[2-[(7-Ethoxy-6-fluoroquinazolin-4-yl)amino]ethyl]phenyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]urea

InChIKey	`DZAPMAGSEHVBQI-UHFFFAOYSA-N`
Compound Name	1-[4-[2-[(7-Ethoxy-6-fluoroquinazolin-4-yl)amino]ethyl]phenyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]urea
Canonical SMILES	`CCOc1cc2ncnc(NCCc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4OC)cc3)c2cc1F`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.76
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P04629	NTRK1	Homo sapiens	Human	PF13855 PF16920 PF07714 PF18613	7.7	IC50	ChEMBL;BindingDB
O14965	AURKA	Homo sapiens	Human	PF00069	6.3	IC50	ChEMBL;BindingDB
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.3	IC50	ChEMBL;BindingDB