Molecule Details
InChIKeyDYLJVOXRWLXDIG-UHFFFAOYSA-N
Compound NameMeclinertant
Canonical SMILESCOc1cccc(OC)c1-c1cc(C(=O)NC2(C(=O)O)C3CC4CC(C3)CC2C4)nn1-c1ccnc2cc(Cl)ccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL6.96
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB06455
Drug NameMeclinertant
CAS Number146362-70-1
Groups investigational
ATC Codes nan
Descriptionnan
Categories: Heterocyclic Compounds, Fused-Ring Receptors, Neurotensin, antagonists & inhibitors
Cross-references: BindingDB: 50248034 ChEBI: 125516 CHEMBL506981 ChemSpider: 106480 Wikipedia: Meclinertant ZINC: ZINC000001482927
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P30989 NTSR1 Homo sapiens Human PF00001 7.9 Kd ChEMBL;BindingDB
Q99523 SORT1 Homo sapiens Human PF15902 PF15901 6.6 IC50 ChEMBL;BindingDB
O95665 NTSR2 Homo sapiens Human PF00001 6.4 Ki ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P30989 NTSR1 Neurotensin receptor type 1 antagonist targets