[3-Chloro-4-(pyridin-2-ylmethoxy)-phenyl]-[7-methoxy-5-(4-methyl-piperidin-1-yloxy)-quinazolin-4-yl]-amine

InChIKey	`DXHVWHPBMGIYNQ-UHFFFAOYSA-N`
Compound Name	[3-Chloro-4-(pyridin-2-ylmethoxy)-phenyl]-[7-methoxy-5-(4-methyl-piperidin-1-yloxy)-quinazolin-4-yl]-amine
Canonical SMILES	`COc1cc(ON2CCC(C)CC2)c2c(Nc3ccc(OCc4ccccn4)c(Cl)c3)ncnc2c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.3
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	8.3	IC50	ChEMBL;BindingDB
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	8.3	pIC50	TTD_MultiTarget