Molecule Details
InChIKeyDWTNLZZEPSCAIH-UHFFFAOYSA-N
Compound Name4-(1-Aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)cyclohexane-1-carboxamide
Canonical SMILESCC(N)C1CCC(C(=O)Nc2ccnc3[nH]ccc23)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)25
Pfam Stratification Cross-Family
Avg pChEMBL6.52
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (25)
Target Gene Organism Category Pfam pChEMBL Type Source
Q04759 PRKCQ Homo sapiens Human PF00130 PF21494 PF00069 PF00433 8.1 Ki ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 7.7 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.6 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.1 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.8 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.8 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.7 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.4 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 6.4 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.3 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.3 Ki ChEMBL
O15530 PDPK1 Homo sapiens Human PF14593 PF00069 6.2 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.2 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P34947 GRK5 Homo sapiens Human PF00069 PF00615 6.2 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 6.2 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 6.0 Ki ChEMBL
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 6.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.0 Ki ChEMBL