Molecule Details
| InChIKey | DWSJBSVHCVJEDX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-(2-Chlorophenyl)-6-methoxy-3-methylimidazo[5,1-c][1,2,4]benzotriazine |
| Canonical SMILES | COc1cccc2c1nnc1c(C)nc(-c3ccccc3Cl)n12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.37 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9Y233 | PDE10A | Homo sapiens | Human | PF01590 PF00233 | 8.6 | IC50 | ChEMBL;BindingDB |
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 7.2 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 7.2 | IC50 | ChEMBL |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 7.2 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 7.2 | IC50 | ChEMBL |
| O00408 | PDE2A | Homo sapiens | Human | PF01590 PF00233 | 7.0 | IC50 | ChEMBL |