Molecule Details
InChIKeyDWPQODZAOSWNHB-UHFFFAOYSA-N
Compound Name1-(3-chlorophenyl)-3-(3-methyl-5-oxo-4H-imidazol-2-yl)urea
Canonical SMILESCN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL7.25
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12931
Drug NameFenobam
CAS Number57653-26-6
Groups investigational
ATC Codes nan
DescriptionFenobam is under investigation in clinical trial NCT00637221 (Open Label Study Investigating Safety and Efficacy of Fenobam anhydrous 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance Tasks, Adults With Fragile X Syndrome).

Cross-references: BindingDB: 50105838 ChEBI: 92728 CHEMBL239800 ChemSpider: 142953 PDB: D7W PubChem:162834 PubChem:347829076 Wikipedia: Fenobam ZINC: ZINC000000001436
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13255 GRM1 Homo sapiens Human PF00003 PF01094 PF10606 PF07562 8.2 Ki ChEMBL
P41594 GRM5 Homo sapiens Human PF00003 PF01094 PF10606 PF07562 7.4 IC50 ChEMBL;BindingDB
Q9UBN7 HDAC6 Homo sapiens Human PF00850 PF02148 6.2 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P41594 GRM5 Metabotropic glutamate receptor 5 allosteric modulator targets