Molecule Details
InChIKeyDWHVZCLBMTZRQM-UHFFFAOYSA-N
Compound Name1H-Pyrazolo[3,4-b]quinoxalin-3-amine
Canonical SMILESNc1n[nH]c2nc3ccccc3nc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL6.84
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 8.0 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 8.0 IC50 ChEMBL;BindingDB
Q00535 CDK5 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 6.4 IC50 ChEMBL;BindingDB
P06493 CDK1 Homo sapiens Human PF00069 6.2 IC50 BindingDB
P49841 GSK3B Homo sapiens Human PF00069 6.0 IC50 ChEMBL;BindingDB