(2R,3S)-5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane

InChIKey	`DWDIQEPGVYBABO-OFNKIYASSA-N`
Compound Name	(2R,3S)-5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Canonical SMILES	`Cn1c(SCCCN2CC[C@]3(C[C@@H]3c3ccc(C(F)(F)F)cc3)C2)nnc1-c1ccncc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.23
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P35462	DRD3	Homo sapiens	Human	PF00001	9.0	Ki	ChEMBL;BindingDB
Q12809	KCNH2	Homo sapiens	Human	PF00027 PF00520 PF13426	6.5	IC50	ChEMBL;BindingDB
P14416	DRD2	Homo sapiens	Human	PF00001	6.2	Ki	ChEMBL;BindingDB