Molecule Details
InChIKeyDVSMVUMYJDOPJQ-UHFFFAOYSA-N
Compound Name5-Methyl-1,5-diazapentacyclo[10.8.1.02,7.08,21.015,20]henicosa-2(7),8,10,12(21),15,17,19-heptaene
Canonical SMILESCN1CCc2c(c3cccc4c3n2-c2ccccc2CC4)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Homologous
Avg pChEMBL6.79
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
P28335 HTR2C Homo sapiens Human PF00001 8.0 Ki ChEMBL
P28223 HTR2A Homo sapiens Human PF00001 7.6 Ki ChEMBL
P35367 HRH1 Homo sapiens Human PF00001 7.3 Ki ChEMBL;BindingDB
P25021 HRH2 Homo sapiens Human PF00001 7.1 Ki ChEMBL;BindingDB
P28221 HTR1D Homo sapiens Human PF00001 7.1 Ki ChEMBL
P41595 HTR2B Homo sapiens Human PF00001 7.1 Ki ChEMBL
P34969 HTR7 Homo sapiens Human PF00001 7.0 Ki ChEMBL
P50406 HTR6 Homo sapiens Human PF00001 6.8 Ki ChEMBL
P18825 ADRA2C Homo sapiens Human PF00001 6.8 Ki ChEMBL
P08913 ADRA2A Homo sapiens Human PF00001 6.6 Ki ChEMBL
P18089 ADRA2B Homo sapiens Human PF00001 6.4 Ki ChEMBL
P21918 DRD5 Homo sapiens Human PF00001 6.2 Ki ChEMBL
P25100 ADRA1D Homo sapiens Human PF00001 6.2 Ki ChEMBL
P08908 HTR1A Homo sapiens Human PF00001 6.2 Ki ChEMBL
P47898 HTR5A Homo sapiens Human PF00001 6.1 Ki ChEMBL
P14416 DRD2 Homo sapiens Human PF00001 6.1 Ki ChEMBL;BindingDB