Molecule Details
| InChIKey | DVNSWDWISPDNHZ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-(4-chlorophenyl)-5-(1,4-dimethyl-1H-benzo[d][1,2,3]triazol-6-yl)-1-isopropyl-2-(tetrahydrofuran-3-yl)-5,6-dihydropyrrolo[3,4-d]imidazol-4(1H)-one |
| Canonical SMILES | Cc1cc(N2C(=O)c3nc(C4CCOC4)n(C(C)C)c3C2c2ccc(Cl)cc2)cc2c1nnn2C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.19 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O60885 | BRD4 | Homo sapiens | Human | PF17035 PF17105 PF00439 | 7.8 | IC50 | ChEMBL;BindingDB |
| Q15059 | BRD3 | Homo sapiens | Human | PF17035 PF00439 | 7.7 | IC50 | ChEMBL;BindingDB |
| Q92793 | CREBBP | Homo sapiens | Human | PF00439 PF09030 PF08214 PF02172 PF23570 PF06001 PF02135 PF00569 | 6.0 | IC50 | ChEMBL;BindingDB |