Molecule Details
InChIKeyDVJAMEIQRSHVKC-BDAKNGLRSA-N
Canonical SMILESO=C(CN[C@@H]1CCNC1)N1CCC[C@H]1B(O)O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.89
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB11723
Drug NameDutogliptin
CAS Number852329-66-9
Groups investigational
ATC Codes nan
DescriptionDutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.
Categories: Acids Acids, Noncarboxylic Agents causing angioedema Blood Glucose Lowering Agents Boron Compounds DPP-IV Inhibitors
Cross-references: ChemSpider: 9428517 PubChem:11253490 PubChem:347828085 ZINC: ZINC000169746730
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P27487 DPP4 Homo sapiens Human PF00930 PF00326 7.6 IC50 ChEMBL;BindingDB
Q86TI2 DPP9 Homo sapiens Human PF19520 PF00930 PF00326 6.2 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P27487 DPP4 Dipeptidyl peptidase 4 inhibitor targets