Molecule Details
InChIKeyDVFCRTGTEXUFIN-GFCCVEGCSA-N
Canonical SMILESCC(C)CCN[C@@H]1CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.81
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB21547
Drug NameOsunprotafib
CAS Number2489404-97-7
Groups investigational
ATC Codes nan
DescriptionOsunprotafib is a small molecule drug. The usage of the INN stem '-protafib' in the name indicates that Osunprotafib is a human protein tyrosine phosphatase (HPTP) inhibitor. Osunprotafib is under investigation in clinical trial NCT04777994 (Study With ABBV-CLS-484 in Participants With Locally Advan...

Categories: Sulfur Compounds Thiazoles
Cross-references: BindingDB: 736420 CHEMBL5095164 PDB: M5R
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P18031 PTPN1 Homo sapiens Human PF00102 8.9 IC50 ChEMBL
P17706 PTPN2 Homo sapiens Human PF00102 8.7 IC50 ChEMBL