N-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-pyrido[3,2-d]pyrimidin-6-yl]-acrylamide

InChIKey	`DTKYOILJQJQIHX-UHFFFAOYSA-N`
Compound Name	N-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-pyrido[3,2-d]pyrimidin-6-yl]-acrylamide
Canonical SMILES	`C=CC(=O)Nc1nc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.4
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	9.0	pIC50	TTD_MultiTarget
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.8	IC50	ChEMBL;BindingDB